Updated November 2026. Label facts checked on 5 November 2026 on each brand's own UK website. Verve makes one of the products below (Spermidine 18mg Capsules), so read the table before you read our view.
Nine UK brands sell spermidine as capsules, and their labels differ in four ways that matter more than the front of the pack: how the amount is written (a wheat germ extract weight with "of which spermidine", a figure for spermidine trihydrochloride, or a figure for spermidine itself), the amount per serving (1.4mg to 18mg), whether a purity figure and a certificate of analysis are given, and what else is in the capsule. Three of the nine state a purity figure; two link a certificate. Spermidine is a polyamine found in wheat germ, soy and aged cheese; that is the chemistry, and this article makes no claim beyond it. Here are the nine UK spermidine products that come up most often, compared on their labels.
The short answer
- Highest stated spermidine per serving, one ingredient plus a plant capsule: Verve Spermidine 18mg Capsules, 18mg of spermidine per capsule from 99% spermidine trihydrochloride, one a day, 30 capsules. Every batch tested for purity; certificate on request.
- Certificate of analysis linked on the page: Longevity Box Pure Spermidine (PDF labelled August 2024; 6mg per two capsules, with zinc and thiamin) and Naturecan Spermidine (5mg per capsule with brown rice flour).
- Purity figure stated on the page: Verve (99% spermidine trihydrochloride), Time Health Renew ("Spermidine 99% (3HCl)", 6.5mg) and Longevity Box ("99%+").
- One capsule a day, two months in a bottle: DoNotAge Pure Spermidine (8mg), Time Health Renew (6.5mg), Naturecan (5mg) and Kiki Health (1.4mg from wheat germ extract), all 60 capsules.
- Wheat germ extract rather than the salt: Kiki Health (700mg extract, of which 1.4mg spermidine, shell only) and Longevity Box (600mg fermented extract standardised to 1%).
- Smallest pack to try: Verve and Charava Spermidine 5mg, both one capsule a day for 30 days.
- Made in the UK on the label: Charava ("UK-made"), Time Health (Uckfield, "made in UK") and Welzo ("made in the UK to GMP standards").
Best spermidine supplement UK: the comparison table
Every column is a label fact taken from the product page. "Not stated" means the page does not give it. Prices are left out on purpose; each brand's current price is on its own site, and the reason is in "How we checked".
| Product | Form | Spermidine per serving | Servings per pack | Stated purity | Testing and certificate of analysis | Other ingredients in the capsule | Storage advice | UK-based brand? | Where sold |
|---|---|---|---|---|---|---|---|---|---|
| Verve Spermidine 18mg Capsules | Capsule | 18mg (1 capsule), stated as spermidine, from 99% spermidine trihydrochloride | 30 (30 capsules) | 99% spermidine trihydrochloride on the label; tested every batch, figure on the certificate, available on request | Every batch tested for purity; certificate of analysis on request | Plant cellulose shell only | Not stated | Yes (Wilmslow, Cheshire) | vavaverve.com (brand also at Boots, Holland & Barrett, Amazon UK; spermidine listing not checked by us) |
| DoNotAge Pure Spermidine | Capsule | 8mg (1 capsule), stated as spermidine | 60 (60 capsules); 366 size also sold | Not stated on the page ("ultra-pure", no figure) | "Third-party tested, batch by batch"; GMP and ISO 9001; no certificate mentioned | Not stated (no ingredient list; "no fillers") | Not stated | Not stated on this page; site shows US dollars | donotage.org, Healf |
| Youth & Earth Liposomal Spermidine | Capsule (liposomal) | 5.49mg per capsule, stated as spermidine; panel serving two capsules (10.98mg); directions say 1 or 2 | 60 capsules (30 at two a day, 60 at one) | Not stated | "Every product is third-party tested"; no certificate visible | Sunflower lecithin (liposomal blend), rice flour; HPMC shell | Away from heat and sunlight, in a closed container | UK store in pounds; address not on the page | youthandearth.com, Healf |
| Kiki Health Spermidine 60 Vegicaps | Capsule | 1.4mg (1 capsule), from 700mg wheat germ extract 15:1 ("of which spermidine 1.4mg") | 60 (60 capsules); directions say 1 or 2 | Not stated (extract "no less than 0.2% natural spermidine") | Powder tested and metal-detected before encapsulation; no third-party wording; no certificate | Hypromellose shell only; contains wheat and gluten | Cool, dry place away from sunlight; fridge not required | Yes (Aylsham, Norfolk) | kiki-health.com; UK retailers list it |
| Charava Spermidine 5mg | Capsule | 5mg (1 capsule); ingredient line says "5mg of Spermidine Trihydrochloride per serving", description says 5mg of spermidine | 30, 60 or 90 days at one a day (capsule count not stated) | Not stated ("high-purity", no figure) | "Each batch is tested for purity, potency, and contaminants"; third-party tested; no certificate mentioned | Hypromellose shell only | Not stated | Yes (UK-made; Infinity Therapeutics Limited) | charava.co.uk |
| Longevity Box Pure Spermidine | Capsule | 6mg (2 capsules), from 600mg fermented wheat germ extract standardised to 1% spermidine | Page says 60 servings; 60 capsules at two a day is 30 | 99%+, every batch | Third-party batch tested in the UK; certificate PDF linked ("Latest Purity Certificate Aug 2024") | Zinc 25mg, thiamin 50mg; HPMC shell | Cool, dry, airtight, dark place | Yes (Poole) | longevitybox.co.uk, Healf |
| Time Health Renew | Capsule (pullulan) | 6.5mg (1 capsule), stated as "Spermidine 99% (3HCl)" | 60 (60 capsules) | 99% (spermidine 3HCl) | Links a heavy metals report for the brown rice flour; GMP; no certificate for the spermidine | Brown rice flour; pullulan (tapioca) shell | Not stated | Yes (Uckfield; made in UK) | timehealth.co.uk |
| Naturecan Spermidine | Capsule | 5mg (1 capsule), stated as spermidine | 60 (60 capsules); 120 and 180 also sold | Not stated in the page text | "Third-party testing at every stage of production"; certificate of analysis PDF linked | Stoneground brown rice flour (bulking agent); HPMC shell | Not stated | Not stated ("Naturecan UK" store; made in Europe) | uk.naturecan.com |
| Welzo Ultra Purity Spermidine | Capsule | 10mg (2 capsules), stated as "pure Spermidine 3HCL"; mg per capsule not stated | 30 (60 capsules) | "100% Spermidine 3HCL"; no separate figure | "Third-party tested for purity"; no certificate mentioned | Shell not named; "no fillers, no binders" | Not stated | Made in the UK (page); company base not stated | welzo.com |
What the nine labels say
The per-serving figures run from 1.4mg to 18mg and are written three ways. Two labels give a wheat germ extract weight and the spermidine inside it (Kiki Health, Longevity Box). Three give a figure for spermidine trihydrochloride, the salt, also written 3HCl (Welzo, Time Health, Charava's ingredient line). Four give a figure for spermidine itself (Verve, DoNotAge, Youth & Earth, Naturecan). Six label one capsule as the serving; Welzo, Longevity Box and Youth & Earth's panel label two. Three state a purity figure. Two link a certificate, Verve supplies one on request, four say third-party tested with nothing to download. Three list a shell and nothing else (Verve, Kiki Health, Charava), three add rice flour, one adds zinc and thiamin, two do not name the shell. Three give a storage line; six, Verve among them, say nothing.
The products in detail
Verve Spermidine 18mg Capsules
Verve Spermidine is the product we make. The label: 18mg of spermidine per capsule, from 99% spermidine trihydrochloride, in a plant cellulose shell. Thirty capsules, one a day. Every batch is tested for purity, and the certificate of analysis for your batch, with the purity figure, is available on request from hello@vavaverve.com. The gaps: the certificate is on request rather than linked (Longevity Box and Naturecan link theirs), there is no storage line. Like Charava, Time Health and Welzo, the capsules are made in the UK. £17.99 one-off (60p a serving), £12.59 a month (42p) or £34.40 a quarter for three packs (38p). Also sold in the Core Renewal Stack. Who it suits: anyone who wants the highest stated figure in the table, one capsule a day, nothing else in the capsule, and a certificate they can ask for.
DoNotAge Pure Spermidine
One of the most-named brands for this question. Each capsule contains 8mg of spermidine, the daily serving is 8mg, and 60 capsules is two months; a 366-capsule size is also sold. "Third-party tested, batch by batch", made to GMP and ISO 9001 standards. The page gives no ingredient list, shell, purity percentage, certificate, storage advice or company location. The site showed us US dollar pricing; Healf, a UK retailer, also lists it. Who it suits: anyone who wants an 8mg capsule once a day from a widely named brand and will take the testing statement without a certificate.
Youth & Earth Liposomal Spermidine
The only liposomal product here. Each capsule provides 5.49mg of spermidine in a sunflower lecithin blend, with rice flour and an HPMC shell. The panel gives a two-capsule serving (10.98mg) while the directions say one or two in the evening, so 60 capsules is 30 or 60 days. No purity figure. "Every product is third-party tested", though we could not see a report. Storage: away from heat and sunlight, in a closed container. The UK store prices in pounds and gives no address; Healf also lists it. Who it suits: anyone who wants a liposomal capsule with the figure stated per capsule and a storage line.
Kiki Health Spermidine 60 Vegicaps
A whole-extract label. Each capsule contains 700mg of wheat germ extract at 15:1, "of which spermidine 1.4mg", standardised to no less than 0.2%. The only other ingredient is the hypromellose shell, and the allergen is stated: contains wheat and gluten. Sixty capsules, labelled 60 servings, though the directions say one to two daily after food. Testing is in-house, before encapsulation; no third-party wording, no certificate. Storage is a cool, dry place away from sunlight; no fridge needed. Based in Aylsham, Norfolk. Who it suits: anyone who wants spermidine as a food extract with the extract weight and the spermidine content both on the label.
Charava Spermidine 5mg
One capsule a day, sold as 30, 60 and 90-day packs. The ingredient line reads "5mg of Spermidine Trihydrochloride per serving", while the description says "5mg of high-purity spermidine per capsule"; the two are not the same figure (see "How to compare"), so ask the brand which it means. Hypromellose shell, "100% filler-free". Each batch is tested for purity, potency and contaminants; no certificate is mentioned and no purity percentage given. No storage advice. UK-made in GMP-certified facilities; the company is Infinity Therapeutics Limited. Who it suits: anyone who wants a UK-made single capsule a day, a shell-only ingredient list and a 30-day pack to start.
Longevity Box Pure Spermidine
The fullest disclosure in the table. Two capsules a day give 6mg of spermidine from 600mg of fermented wheat germ extract standardised to 1%, plus 25mg of zinc and 50mg of thiamin, in an HPMC shell. Purity is 99%+, every batch independently tested in the UK, with the certificate linked as "Latest Purity Certificate Aug 2024". Two things to check: the page says 60 servings, but 60 capsules at two a day is 30; and the FAQ gives zinc as 50mg where the ingredient line says 25mg. Storage is a cool, dry, airtight, dark place. Longevity Box is in Poole; Healf also sells it. Who it suits: anyone who wants a wheat germ extract with a purity figure and a certificate to read first, and does not mind zinc and thiamin in the capsule.
Time Health Renew
The label reads "6.5mg Spermidine 99% (3HCl)" per capsule, so the figure is for the trihydrochloride salt at 99% purity; one a day with food, 60 capsules. Other ingredients: brown rice flour and a pullulan (tapioca) capsule. The "Third Party Test Report" on the page is a heavy metals analysis for the rice flour, not a certificate for the spermidine. Made in the UK to GMP standards; no storage advice; based in Uckfield, East Sussex. Who it suits: anyone who wants a UK-made 3HCl capsule with the purity figure on the label and two months in a bottle.
Naturecan Spermidine
Five milligrams of spermidine per capsule, one a day, 60 capsules, with 120 and 180 sizes also sold. The ingredient list is spermidine, stoneground brown rice flour as a bulking agent and an HPMC capsule. Third-party tested at every stage of production, with a certificate of analysis linked; the page text gives no purity percentage. No storage advice. The store is "Naturecan UK"; made in Europe; no address given. Who it suits: anyone who wants a 5mg capsule a day with a certificate they can open before ordering.
Welzo Ultra Purity Spermidine
Two capsules a day give "10mg pure Spermidine 3HCL per serving", so the figure is for the salt; milligrams per capsule are not stated. The ingredient list is one line, "100% Spermidine 3HCL", with no shell named; the page says no fillers, binders or bulking agents. Sixty capsules, 30 servings. Third-party tested for purity and made in the UK to GMP standards; no certificate is mentioned. No storage advice. Who it suits: anyone who wants a 10mg 3HCl serving, made in the UK, and will check the physical label for the shell.
Others you will see named
Oxford Healthspan's Primeadine Original comes up often: 1mg of spermidine per three-capsule serving from defatted wheat germ extract, with cluster dextrin, sodium citrate and a hypromellose capsule, about 40mg of gluten per serving, 90 capsules, with lab reports linked. It is here rather than in the table because the brand's own site prices in US dollars and gives a US phone number; Healf stocks it in the UK. Feel Supreme's spermidine and astaxanthin combination, sold through Superdrug and Holland & Barrett, is two compounds in one capsule, and we found no brand page to read. spermidineLIFE is Austrian, sold in the UK through importers. Omre's UK address redirects to a US site. ProHealth Longevity, Double Wood, Renue by Science, Codeage and Toniiq are US brands sold through UK retailers. We found no spermidine product at NMN Bio.
How to compare spermidine supplements
- Read which figure the label gives. Labels use three conventions. A wheat germ extract weight with "of which spermidine" (Kiki Health, Longevity Box). A figure for spermidine trihydrochloride, also written 3HCl, the salt (Welzo, Time Health, Charava's ingredient line). Or a figure for spermidine itself (Verve, DoNotAge, Youth & Earth, Naturecan). Spermidine is about 57% of the trihydrochloride by weight, so 10mg of the salt holds about 5.7mg of spermidine, and 18mg of spermidine needs about 32mg of the salt. Where one page uses both words for one figure, ask the brand which it means.
- Dose per serving, then per capsule, then servings. Welzo and Longevity Box label two capsules as a serving; Youth & Earth's panel says two and its directions one or two; the rest label one. Sixty capsules is 60 servings at one a day and 30 at two.
- Is a purity figure stated? Three of the nine give one: Verve (99%), Time Health (99%) and Longevity Box (99%+). For a wheat germ extract the equivalent is the standardisation (Kiki Health: no less than 0.2%; Longevity Box: 1%). "Ultra-pure", "high-purity" and "100%" are not figures.
- Is a certificate of analysis available, and how? Longevity Box and Naturecan link one. Verve supplies yours on request. Time Health links a heavy metals report for its rice flour, not for the spermidine. DoNotAge, Youth & Earth, Charava and Welzo say third-party tested with nothing to download. Kiki Health describes in-house testing.
- What else is in the capsule. Shell only: Verve, Kiki Health, Charava. Rice flour added: Youth & Earth (with sunflower lecithin), Time Health, Naturecan. Zinc and thiamin added: Longevity Box. Shell not named: DoNotAge, Welzo. A wheat germ extract carries wheat; Kiki Health states gluten.
- Storage. Three brands give a line (Youth & Earth, Kiki Health, Longevity Box: cool, dry, out of the light). Six, including Verve, say nothing.
- Price the plan you will actually be on. One-off, monthly and quarterly plans differ. Check each brand's site for today's price; we have not compared prices in this article.
Spermidine supplements: your questions
How much spermidine per serving do UK brands put in a capsule?
From 1.4mg to 18mg, as labelled. Kiki Health labels 1.4mg from 700mg of wheat germ extract. Charava, Naturecan and Youth & Earth label about 5mg per capsule. Longevity Box labels 6mg per two capsules, Time Health 6.5mg, DoNotAge 8mg, Welzo 10mg per two capsules and Verve 18mg. Some of those figures are for the trihydrochloride salt, so read the next answer before lining them up. This is what the labels say, not a recommendation.
What is the difference between spermidine, spermidine trihydrochloride and wheat germ extract on a label?
Spermidine is the compound. Spermidine trihydrochloride (3HCl) is its salt; spermidine is about 57% of its weight, so a 10mg 3HCl figure is about 5.7mg of spermidine. A wheat germ extract label gives the weight of the extract and the spermidine inside it, as a percentage (Longevity Box: 600mg at 1%) or an "of which" line (Kiki Health: 700mg, of which 1.4mg). Verve's label gives the spermidine figure, 18mg, and names the raw material, 99% spermidine trihydrochloride. Welzo and Time Health give the 3HCl figure. Charava's page uses both words for one figure.
Which UK spermidine products publish a certificate of analysis?
Two link one on the product page: Longevity Box (a PDF labelled "Latest Purity Certificate Aug 2024") and Naturecan. Verve supplies the certificate for your batch, with its purity figure, on request from hello@vavaverve.com. Time Health links a heavy metals analysis for its rice flour, not a spermidine certificate. DoNotAge, Youth & Earth, Charava and Welzo state third-party testing without a certificate; Kiki Health describes testing before encapsulation.
Does Verve's spermidine contain anything other than spermidine?
No. The label lists 18mg of spermidine per capsule, from 99% spermidine trihydrochloride, and a plant cellulose capsule shell: no rice flour, no zinc or thiamin, no lecithin, no blend. One capsule a day, 30 capsules. Every batch is tested for purity and the certificate for your batch is available on request from hello@vavaverve.com.
Where can I buy spermidine in the UK?
All nine sell direct from their own websites; Healf, a UK retailer, also stocks Longevity Box, Youth & Earth and DoNotAge. Verve as a brand is also sold at Boots, Holland & Barrett and Amazon UK; we have not checked the spermidine listing at each. Verve Spermidine 18mg Capsules is £17.99 one-off, £12.59 a month or £34.40 a quarter for three packs at vavaverve.com.
How we checked
Every label fact above was taken from the brand's own website on 5 November 2026: vavaverve.com, donotage.org, youthandearth.com, kiki-health.com, charava.co.uk, longevitybox.co.uk, timehealth.co.uk, uk.naturecan.com and welzo.com, using the store's own product data feed where a page would not render. Healf.com was also read as a UK stockist. Where a page did not state a figure we have written "Not stated" rather than guessing, and we have not repeated any brand's claims about what spermidine does. Prices are deliberately not compared here: they change weekly and promotions distort them. Every brand's current price is on its own site. Verve makes Spermidine 18mg Capsules; the table is label facts, our opinion is in the text.
Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. The mention of other brands is for comparison only. All trademarks belong to their respective owners.
